A process for producing crystalline atorvastatin calcium

Details A process for producing crystalline atorvastatin calcium A process for producing crystalline atorvastatin calcium

C - Chemistry, Metallurgy

07

D

C07D 207/34 (2006.01)

Patent

CA 2391357

A factory scale process for producing crystalline atorvastatin calcium includes the step of drying the isolated product in a vacuum pan dryer. The vacuum pan dryer has an agitator which is continuously rotated at a speed of approximately 1 rpm. High quality material is routinely and consistently produced with reduced cycle time.

L'invention concerne un procédé amélioré pour produire de l'atorvastatine calcique cristallin à l'échelle d'une fabrique, le procédé consistant à sécher le produit isolé dans un séchoir à vide. Le séchoir à vide comprend un agitateur qui tourne à une vitesse continue d'à peu près 1 tour par minute. On produit de façon régulière et constante du matériau de bonne qualité avec un temps de cycle réduit.

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