A process for producing solid drug forms

A - Human Necessities – 61 – K

Patent

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A61K 9/20 (2006.01) A61J 3/06 (2006.01) A61K 9/16 (2006.01) A61K 31/19 (2006.01) A61K 31/275 (2006.01) A61K 31/40 (2006.01) A61K 31/455 (2006.01) A61K 31/60 (2006.01) A61K 47/32 (2006.01) A61K 47/38 (2006.01)

Patent

CA 2232357

The invention concerns a method of producing medicaments in solid form by mixing at least one pharmacologically acceptable polymer binder, at least one pharmaceutical active substance and optionally conventional pharmaceutical additives, extruding the mixture and shaping the medicament, a pre-mixture being prepared from the components and fed into the extruder. The method according to the invention enables high-quality medicaments to be produced in a simple and careful manner.

L'invention concerne un procédé de préparation de formes galéniques solides par mélange d'au moins un liant polymère pharmaceutiquement acceptable, d'au moins un principe actif pharmaceutique et éventuellement d'additifs pharmaceutiques classiques, par extrusion du mélange et par moulage de la forme galénique, un mélange préliminaire étant préparé à partir des constituants et introduit dans l'extrudeuse. Ce procédé permet d'obtenir des formes galéniques de haute qualité, selon un mode de production aisé qui n'altère pas les produits.

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