A process for regulating vagal tone

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/70 (2006.01) A61K 31/00 (2006.01) A61K 31/675 (2006.01)

Patent

CA 2239780

The present invention provides methods of altering vagal tone in a patient by administering a therapeutically effective amount of a mediator of P2x-purinoceptors located on vagal afferent nerve terminals to the patient. Diagnostic applications are also provided.

L'invention concerne des procédés pour modifier la tonus vagal chez un patient, en lui administrant une quantité suffisante, pour avoir un effet thérapeutique, d'un médiateur des purinorécepteurs P2x situés sur les terminaisons afférentes du nerf vague. L'invention concerne également des utilisations diagnostiques.

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