C - Chemistry – Metallurgy – 09 – K
Patent
C - Chemistry, Metallurgy
09
K
C09K 15/06 (2006.01) A61K 7/48 (2000.01)
Patent
CA 2379511
The present invention is directed to a process for stabilizing antioxidant compounds comprising the step of adding to said compound, in an aqueous mean, at least an oxygen-removing compound, at least a metallic ion sequestering compound and at least an oxidation reaction reversing compound. The invention is particularly useful to stabilize antioxidant compounds such as levogyrous ascorbic acid (LAA), popularly known as "Vitamin C", and the LAA associated with proanthocyanidins (OPC) for the preparation of pharmaceutical and cosmetic compositions.
La présente invention concerne un procédé de stabilisation de composés antioxydants consistant à ajouter aux composés, dans un milieu aqueux, au moins un composé retirant l'oxygène, au moins un composé séquestrant les ions métalliques et au moins un composant inversant une réaction d'oxydation. L'invention est particulièrement utile dans la stabilisation de composés antioxydants tels que l'acide ascorbique lévogyre (LAA), plus connu sous le nom de </= vitamine C >/= , et l'acide ascorbique lévogyre associé aux proantocianidines (OPC) pour la préparation de compositions pharmaceutiques et cosmétiques.
Alcantara Martins Zucchetti Roberto
Araujo Macian Karla
Chitarra Souza Simoni
Fanan Simone
Fuscelli Pytel Rodrigo
Industria E. Comercio de Cosmeticos Natura Ltda.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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