A process for the crystallization of non-sucrose substances

C - Chemistry – Metallurgy – 07 – B

Patent

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C07B 63/00 (2006.01) C13B 20/16 (2011.01) C13B 30/02 (2011.01) C07D 201/16 (2006.01)

Patent

CA 2398295

The invention relates to a process for the crystallization of substances having a narrow metastable supersaturation zone. In the process the saturation of a solution is gradually increased and the solution is seeded for the crystallization. The seeding is performed at a seeding point which is selected in response to a signal received from said process indicating imminent or initial spontaneous nucleation. The process provides a good crystal yield and a crystalline product having a uniform crystal structure and a narrow crystal size distribution.

L'invention concerne un procédé de cristallisation de substances possédant une zone de sursaturation métastable étroite. Ce procédé consiste à augmenter graduellement la saturation d'une solution et à ensemencer cette dernière afin d'obtenir une cristallisation. On effectue l'ensemencement à un point sélectionné en réaction à un signal émis en cours de procédé et indiquant une nucléation spontanée imminente ou initiale. Ce procédé est très productif en cristaux et permet d'obtenir un produit cristallin dont la structure est uniforme et la dimension des cristaux étroitement répartie.

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