A process for the isolation of 10-deacetyl baccatin iii from...

Details A process for the isolation of 10-deacetyl baccatin iii from... A process for the isolation of 10-deacetyl baccatin iii from...

C - Chemistry, Metallurgy

07

D

C07D 305/14 (2006.01)

Patent

CA 2354847

A novel process for isolation 10-deacetyl baccatin-III (10-DAB) and also complete separation of paclitaxel present in the primary extract, on a commercial scale from plant extract of Taxus species by solvent crystallization without employing chromatographic separation.

L'invention concerne un nouveau procédé d'isolement de baccatin III 10-déacétyle (10-DAB) et de séparation totale du paclitaxel présent dans l'extrait primaire, à l'échelle commerciale, à partir d'un extrait végétal de l'espèce Taxus, le procédé consistant à effectuer une cristallisation aux solvants sans séparation chromatographique.

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