A process for the microbial production of aromatic amino...

Details A process for the microbial production of aromatic amino... A process for the microbial production of aromatic amino...

C - Chemistry, Metallurgy

12

P

C12P 13/22 (2006.01) C12N 9/00 (2006.01) C12N 15/52 (2006.01)

Patent

CA 2484379

The invention relates to a method for the microbial production of aromatic amino acids and other metabolites of the aromatic amino acid biosynthetic pathway. Microbially produced substances such as fine chemicals, particularly aromatic amino acids or metabolites of the aromatic biosynthetic pathway, are or great economic interest, and there is an increasing demand for amino acids, for example. According to the inventive method, a pyc gene sequence is introduced into microorganisms, whereupon aromatic amino acids and metabolites of the aromatic biosynthetic pathway can be produced in an improved manner. The inventive method is particularly suitable for producing L-Phenylalanine.

L'invention concerne un procédé de production microbienne d'aminoacides aromatiques et d'autres métabolites de la voie de biosynthèse des aminoacides aromatiques. Les substances élaborées de manière microbienne, telles que les produits chimiques fins, en particulier les aminoacides aromatiques ou des métabolites de la voie de biosynthèse des aromatiques sont très intéressantes du point de vue économique, dans un contexte d'augmentation de la demande en aminoacides par exemple. Selon l'invention, des aminoacides aromatiques ainsi que des métabolites de la voie de biosynthèse des aromatiques peuvent être produits de manière améliorée après introduction d'une séquence génique de la pyc dans des micro-organismes. Le procédé de l'invention convient en particulier à la production de L-phénylalanine.

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