A process for the preparation of...

Details A process for the preparation of... A process for the preparation of...

C - Chemistry, Metallurgy

07

C

C07C 229/08 (2006.01) C07C 227/22 (2006.01) C07C 243/28 (2006.01)

Patent

CA 2644624

A process for the preparation of a compound of formula (I), (see formula I) comprising: a) the reaction of a compound of formula (II) (see formula II) with hydrazine to obtain a compound of formula (III), (see formula III) b) the conversion of a compound of formula (III) by rearrangement via formation of nitrene/isocyanate, in a solvent of formula R1-OH, wherein R1 is as herein defined, to obtain a compound of formula (IV); (see formula IV) c) the enantiomeric enrichment of a compound of formula (IV) to obtain the enantiomer (S) of a compound of formula (V) (see formula V) d) the hydrolysis of a compound of formula (V).

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