A process for the preparation of...

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C - Chemistry, Metallurgy

07

C

C07C 237/46 (2006.01) C07C 231/14 (2006.01)

Patent

CA 2351717

A novel process for the preparation of N,N'-bis[2, 3-dihydroxypropyl] -5-[ (hydroxyacetyl) methylamino]-2, 4,6-triiodo-1, 3-benzenedi carboxamide of formula (I), commonly known as lomeprol, a novel non-ionic contrast agent which shows very good safety and contrast effectiveness.

L'invention a pour objet un nouveau procédé de préparation de N,N'-bis¬2,3-dihydroxypropyl|-5- ¬(hydroxyacétyl)méthylamino|-2,4,6-triiodobenzène-1,3-dicarboxamide, de formule (I), communément appelé ioméprol, qui est un nouvel agent de contraste non ionique présentant d'excellentes caractéristiques en matière de sécurité et d'efficacité de contraste.

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