A process for the preparation of...

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A61K 31/4035 (2006.01) A61K 31/4045 (2006.01) A61P 25/16 (2006.01) C07D 209/34 (2006.01) C07D 209/48 (2006.01) C07D 403/06 (2006.01)

Patent

CA 2548982

The present invention discloses a novel process and novel intermediates for the Preparation of 4-[2-(di -n-propyl amino) ethyl]-1,3-dihydro-2H-indol-2- one, commonly known as Ropinirole (I) and pharmaceutical composition comprising the same. Further the present invention also discloses a method of treatment for cardiovascular disorders and Parkinson~s disease.

L'invention concerne un nouveau procédé et de nouveaux intermédiaires servant à préparer 4-[2-(di-n-propylamino)éthyl]-1,3-dihydro-2H-indol-2-one, désigné communément ropinirole (I), ainsi qu'une composition pharmaceutique contenant ce dernier. Elle concerne également une méthode servant à traiter des maladies cardio-vasculaires et la maladie de Parkinson.

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