C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 215/14 (2006.01)
Patent
CA 2666208
This invention relates to a process for the preparation of 3-[2-(7-chloro-2- quinolinyl)ethenyl]benzaldehyde (II) which comprises of; a) reacting 7-chloroquinaldine (III) with isopthaldehyde (IV) in the presence of a base, acid or a combination thereof in a single organic solvent b) isolating the crude intermediate by filtration from the reaction mixture c) purifying the wet crude to remove the bis adduct of formula (V) by crystallization from an organic solvent. (see formula II)
Chatterjee Sugata
Chavda Mukesh
Kadu Rushikesh
Kumar Neeraj
Rawat Ajay Singh
Borden Ladner Gervais Llp
Sterling Biotech Limited
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