A process for the preparation of...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 333/20 (2006.01)

Patent

CA 2640212

Provided is a process for preparing a duloxetine intermediate,(S)-(+)-N,N- Dimethyl-3-(1- naphthalenyloxy)-3-(2-thienyl)propanamine (DNT), and its conversion to duloxetine or a pharmaceutically acceptable salt thereof.

L'invention concerne un procédé de préparation d'un intermédiaire de la duloxétine, (5)-(+)-N,N-Diméthyl-3-(l- naphthalényloxy)-3-(2-thiényl)propanamine (DNT), et sa transformation en duloxétine ou en un sel pharmaceutiquement acceptable de celle-ci.

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