A process for the preparation of 6.alpha.-fluoro steroids by...

C - Chemistry – Metallurgy – 07 – J

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C07J 3/00 (2006.01) A61P 29/00 (2006.01) C07J 31/00 (2006.01) C07J 71/00 (2006.01) C07J 75/00 (2006.01)

Patent

CA 2480629

The process for the preparation of 6.alpha.-fluoro steroids, comprising the reaction of the corresponding 6.beta.-fluoro steroids, or of 6.alpha./6.beta. isomeric mixtures with an organic base having a diazo iminic group, in a suitably selected organic solvent, is described.

L'invention concerne un procédé de préparation de 6?-fluoro stéroïdes consistant à faire réagir les 6?-fluoro stéroïdes correspondants ou des mélanges isomères 6?/6? avec une base organique possédant un groupe diazo iminique, dans un solvant organique sélectionné de manière appropriée.

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