A process for the preparation of eserethole

Details A process for the preparation of eserethole A process for the preparation of eserethole

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) C07C 233/25 (2006.01) C07D 209/34 (2006.01)

Patent

CA 2136972

2136972 9324455 PCTABS00028 A process for the preparation of 1,3-dimethyl-5-hydroxy-oxindole of formula (II) which comprises the reaction of 4-(N-methylamino)phenol with 2-halogen-propinol chloride and cyclization of the resulting compound in the presence of Lewis acids, and the conversion thereof to eserethole.

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