A process for the preparation of (-)-eserethole from...

Details A process for the preparation of (-)-eserethole from... A process for the preparation of (-)-eserethole from...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01)

Patent

CA 2141456

A process for the preparation of (-)-eserethole, of formula (I) starting from (~)-eserethole, or from mixtures of (+)-and (-)-eserethole in which the latter enantiomer prevails by treating (~)- eserethole or mixtures of (~)- and (-)-eserethole enriched in the latter enantiomer, with 0.5-0.7 mole (per mole of the enantiomeric mixture) of a resolution agent, to yield a (-)-eserethole salt less soluble than the corresponding (+)-eserethole salt.

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