A process for the preparation of esters of...

Details A process for the preparation of esters of... A process for the preparation of esters of...

C - Chemistry, Metallurgy

07

D

C07D 295/15 (2006.01) C07D 295/088 (2006.01)

Patent

CA 2269394

The invention provides a process for the preparation of esters [2-[4-[(4-chlorophenyl) phenylmethyl]-1-piperazinyl]ethoxy]acetic acid, of the formula (I) (see formula I) wherein X represents a halogen atom and R represents a lower alkyl group comprising reacting: (a) a compound of the formula (II) (see formula II) (b) a compound of the formula (III) (see formula III) and (c) a tertiary amine as a solvent and as an acid scavenger at a temperature of at least 100°C, wherein X is a halogen atom, X' is selected from the group consisting of bromine and chlorine and R is a lower alkyl group.

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