C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 231/02 (2006.01) C07C 227/04 (2006.01) C07C 227/18 (2006.01)
Patent
CA 2430293
The invention relates to a process for the preparation of a compound of formula (I), wherein R represents a 2,3-dihydroxy-1-propyl or a 1,3-dihydroxy- 2-propyl radical, via direct amidation of a dialkyl ester of 5-amino-1,3- benzenedicarboxylic acid of formula (V), wherein R1 represents a straight or branched (C1-C4)-alkyl group, with at least the stoichiometric amount of an amine of formula H2NR.
L'invention concerne un procédé de préparation d'un composé correspondant à la formule (I), dans laquelle R représente un 2,3-dihydroxy-1-propyle ou un radical 1,3-dihydroxy-2-propyle, obtenu par amidation directe d'un dialkylester de l'acide 5-amino-1,3-benzènedicarboxylique correspondant à la formule (V), dans laquelle R¿1? représente un groupe alkyle C¿1?-C¿4?, droit ou ramifié, avec au moins la quantité stoechiométrique d'une amine possédant la formule H¿2?NR.
Anelli Pier Lucio
Brocchetta Marino
Cappelletti Enrico
Lux Giovanna
Bracco Imaging S.p.a.
Kirby Eades Gale Baker
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