A process for the preparation of n,n'-substituted...

C - Chemistry – Metallurgy – 07 – C

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C07C 231/02 (2006.01) C07C 227/04 (2006.01) C07C 227/18 (2006.01)

Patent

CA 2430293

The invention relates to a process for the preparation of a compound of formula (I), wherein R represents a 2,3-dihydroxy-1-propyl or a 1,3-dihydroxy- 2-propyl radical, via direct amidation of a dialkyl ester of 5-amino-1,3- benzenedicarboxylic acid of formula (V), wherein R1 represents a straight or branched (C1-C4)-alkyl group, with at least the stoichiometric amount of an amine of formula H2NR.

L'invention concerne un procédé de préparation d'un composé correspondant à la formule (I), dans laquelle R représente un 2,3-dihydroxy-1-propyle ou un radical 1,3-dihydroxy-2-propyle, obtenu par amidation directe d'un dialkylester de l'acide 5-amino-1,3-benzènedicarboxylique correspondant à la formule (V), dans laquelle R¿1? représente un groupe alkyle C¿1?-C¿4?, droit ou ramifié, avec au moins la quantité stoechiométrique d'une amine possédant la formule H¿2?NR.

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