A process for the preparation of pharmaceutical grade...

Details A process for the preparation of pharmaceutical grade... A process for the preparation of pharmaceutical grade...

C - Chemistry, Metallurgy

07

C

C07C 229/28 (2006.01) C07C 227/40 (2006.01)

Patent

CA 2371210

Process for producing gabapentine of pharmaceutical grade, comprising neutralizing an alcoholic solution of gabapentine chlorhydrate with basic ion exchange resins and insulating directly the gabapentine, without requiring neither the formation nor the isolation of intermediates which are different from the pharmaceutical grade product.

L'invention concerne un procédé de préparation de gabapentine à usage pharmaceutique, consistant à neutraliser une solution d'alcool et de chlorhydrate de gabapentine avec des résines d'échange d'ions de base, puis à isoler directement la gabapentine, sans nécessité de former ou d'isoler des intermédiaires différents du produit à usage pharmaceutique.

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