A process for the preparation of phenyltetrazole derivatives

Details A process for the preparation of phenyltetrazole derivatives A process for the preparation of phenyltetrazole derivatives

C - Chemistry, Metallurgy

07

D

C07D 257/04 (2006.01) C07F 3/02 (2006.01) C07F 5/02 (2006.01)

Patent

CA 2534892

A process for the preparation of phenyltetrazole derivatives of formula (II) wherein R and Y are as defined in the disclosure, by direct ortho-metallation of (tetrazol-5-.gamma.l)benzene. The compounds of formula (II) are useful intermediates for the preparation of angiotensin II antagonists.

L'invention concerne un procédé de préparation de dérivés de phényltétrazole de formule (II), dans laquelle R et Y ont la signification indiquée dans la description, par ortho-métallation directe de (tétrazol-5-yl)benzène. Lesdits composés de formule (II) sont des intermédiaires utiles pour la préparation d'antagonistes de l'angiotensine II.

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