A process for the preparation of the stable, amorphous...

C - Chemistry – Metallurgy – 07 – D

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C07D 475/04 (2006.01)

Patent

CA 2686519

The present invention relates to a process for preparing the stable, amorphous calcium salt of (6S)-N(5)-methyl-5,6,7,8-tetrahydrofolic acid. The present invention also relates to a process for preparing stable, crystalline (6S)-N(5)-methyl-5,6,7,8-tetrahydrofolic acid. The present invention also relates to a process for preparing an aqueous solution of the calcium salt of (6S)-N(5)-methy1-5,6,7,8-tetrahydrofolic acid.

L'invention concerne un procédé de fabrication du sel de calcium amorphe, stable, d'acide (6S)-N-(5)-méthyl-5,6,7,8-tétrahydrofolique. L'invention concerne également un procédé de fabrication d'acide (6S)-N-(5)-méthyl-5,6,7,8-tétrahydrofolique cristallin, stable. L'invention concerne également un procédé de fabrication d'une solution aqueuse du sel de calcium d'acide (6S)-N-(5)-méthyl-5,6,7,8-tétrahydrofolique.

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