A process for the preparation of tolterodine and...

Details A process for the preparation of tolterodine and... A process for the preparation of tolterodine and...

C - Chemistry, Metallurgy

07

D

C07D 311/20 (2006.01) C07C 215/54 (2006.01)

Patent

CA 2502640

A process for the preparation of 6-methyl-4-(R)-phenyl-chroman-2-one and 6-methyl-4-(S)-phenyl-chroman-2-one, intermediates for the synthesis of tolterodine and its (S) enantiomer, by reaction of 6-methyl-coumarin with phenylboronic acids, esters and derivatives thereof, in the presence of chiral catalysts.

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