A process for the purification of opacifying contrast agents

Details A process for the purification of opacifying contrast agents A process for the purification of opacifying contrast agents

B - Operations, Transporting

01

D

B01D 15/08 (2006.01) A61K 49/04 (2006.01) B01D 61/02 (2006.01)

Patent

CA 2247029

A process for the purification of opacifying contrastographic agents, comprising chromatographic and nanofiltration techniques combined together, the subsequent chromatographic separation of the crude product solution and a nanofiltration step, with a final deionization on ion exchange resins.

L'invention concerne un procédé de purification d'agents de contraste opacifiants, consistant à combiner des techniques de chromatographie et de nanofiltration. La solution du produit brut est d'abord soumise à un fractionnement par chromatographie et cette opération est suivie par une nanofiltration et finalement par une déionisation sur résines échangeuses d'ions.

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