A ranitidine tablet having a hydroxypropylmethylcellulose...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/34 (2006.01) A61K 9/28 (2006.01) A61K 9/36 (2006.01) A61K 31/341 (2006.01) A61K 47/38 (2006.01)

Patent

CA 2187323

A ranitidine tablet containing at least 30 % ranitidine hydrochloride is provided with a coating which comprises hydroxypropyl- methylcellulose and ethylcellulose in a mutual weight ratio between 10:1 and 1:2. The coating is produced by applying and drying of a solution of the components of the coating in an aqueous 72.5-82.5% by weight alcohol.

Un comprimé contenant au moins 30 % d'hydrochlorure de ranitidine est pourvu d'un enrobage comprenant de l'hydroxypropylméthylcellulose et de l'éthylcellulose selon un rapport pondéral compris entre 10:1 et 1:2. Cet enrobage est obtenu par application et dessiccation d'une solution des constituants de l'enrobage dans un alcool aqueux d'une teneur de 72,5 à 82,5 % en poids.

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