A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 27/00 (2006.01) A61L 15/40 (2006.01) A61L 15/64 (2006.01) A61L 27/36 (2006.01) A61L 31/00 (2006.01)
Patent
CA 2173547
Disclosed is a raw membrane material for medical materials, which is of acellular nature and consists essentially of a compact layer with a characteristic matrix structure retained and which is produced by dissolving and removing cellular layers including epithelium and fibroblast layers from biogenic connective tissue membrane which comprises epithelial, basement membrane, compact and fibroblast layers. To remove epithelium and fibroblast layers, biogenic connective tissue is treated with an aqueous solution of a quaternary ammonium salt of the formula: [C6H5CH2N(CH3)2R]+Cl- (wherein R is an alkyl group of 8 to 18 carbon atoms) and then with thiolprotease which is a glycoprotein and has a molecular weight of about 26,000 and an isoelectric point of 9 and thereafter is subjected to ultrasonic washing. The membrane material, when used in the medical field, stimulates the growth of tissue cells and is decomposed and absorbed in living body as damaged tissues regenerate.
Kondoh Kazuo
Nakagawa Tokuzo
Yui Tooru
Bio-Engineering Laboratories Ltd.
Smart & Biggar
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