A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61K 31/475 (2006.01) A61K 39/21 (2006.01) A61P 31/14 (2006.01) A61P 31/18 (2006.01) A61P 37/02 (2006.01)
Patent
CA 2431954
The present inventor has noted that at least two populations of immune cells are produced in response to retroviruses which infect mammals. More particularly, the immune system of a mammal infected with a retrovirus is capable of mounting an immune response against the virus through a group of cells herein generally referred to as "effector cells", however, a second population of cells are also produced which regulate the "effector cells", herein generally referred to as "regulator cells", limiting the mammals' ability to effectively control or eradicate the retroviral infection. Accordingly, the present invention utilizes these observations to provide methods for treating a mammal with a retroviral infection.
Cette invention découle de la découverte selon laquelle au moins deux populations de cellules immunitaires sont produites en réaction à la présence de rétrovirus infectant des mammifères. Plus précisément, le système immunitaire d'un mammifère infecté par un rétrovirus est capable d'induire une réaction immunitaire contre ce virus par le truchement d'un groupe de cellules dénommées ici <= cellules effectrices >=. Une seconde population de cellules, nommées <= cellules régulatrices >=, est, toutefois, produite, laquelle population régule les <= cellules effectrices >= en limitant la capacité du mammifère à agir efficacement sur l'infection rétrovirale ou à l'éradiquer. Cette invention tire donc partie de ces observations pour présenter des méthodes de traitement de mammifères atteints d'une infection rétrovirale.
Immunaid Pty Ltd
Smart & Biggar
LandOfFree
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