A sample presentation apparatus for mass spectrometry

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/37 (2006.01) C07K 1/10 (2006.01) C12M 1/40 (2006.01) C12N 9/48 (2006.01) C12N 11/00 (2006.01) C12N 11/14 (2006.01) G01N 1/28 (2006.01) G01N 33/483 (2006.01) G01N 33/543 (2006.01) H01J 49/04 (2006.01) H01J 49/26 (2006.01) H01J 49/40 (2006.01)

Patent

CA 2221250

A sample presentation device, with a surface-bound complex including at least one molecule which chemically modifies a biomolecule, is prepared and exposed to a biomolecule. The molecular weight of the chemically modified biomolecule is then determined by mass spectrometry.

La présente invention se rapporte à un dispositif de présentation d'échantillons, comprenant un complexe fixé à la surface, ledit complexe comportant au moins une molécule qui modifie chimiquement une biomolécule. Ce dispositif est préparé et exposé à une biomolécule. Les poids moléculaires de la biomolécule chimiquement modifiée sont alors déterminés par spectrométrie de masse.

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