A schizophrenic model animal with sensorimotor and...

A - Human Necessities – 01 – K

Patent

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Details

A01K 67/027 (2006.01) C07K 14/485 (2006.01) C12N 15/85 (2006.01) G01N 33/15 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2393680

To provide an animal showing chronic abnormality in cognitive behaviors closely similar to schizophrenia, an animal showing schizophrenia-like abnormality in cognitive behaviors is constructed by administering a specific protein factor inhibiting the brain function development to an immature animal in the development stage. The abnormality in cognitive behavior observed in this animal, which is closely similar to schizophrenia, is useful in developing remedies and diagnostics for schizophrenia.

L'invention se rapporte à l'élaboration d'un animal présentant une anomalie chronique dans ses comportements cognitifs s'apparentant étroitement à la schizophrénie. Pour produire un tel animal présentant une anomalie de type schizophrénie dans ses comportements cognitifs, on administre à un animal immature au stade de développement un facteur protéique spécifique inhibant le développement des fonctions cérébrales. L'anomalie qui est observée chez cet animal s'agissant de son comportement cognitif et qui s'apparente étroitement à la schizophrénie, s'avère utile à la mise au point de remèdes contre la schizophrénie ainsi qu'à l'élaboration de procédures permettant de diagnostiquer la schizophrénie.

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