A screening method of drug for treatment of neuropathic pain

Details A screening method of drug for treatment of neuropathic pain A screening method of drug for treatment of neuropathic pain

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 31/7088 (2006.01) A61K 39/395 (2006.01) A61P 25/02 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01) G01N 33/567 (2006.01)

Patent

CA 2444161

The present invention relates to a screening method for a compound useful for treatment of neuropathic pain, and therapy for the treatment of neuropathic pain. The screening method comprises determining inhibitory activity on the action of P2X~ receptor or inhibitory activity on the activation of microglia, of test compounds. The pharmaceutical composition and the therapy employ a P2X4 receptor inhibitor or a microglial activation-inhibitor as active ingredient.

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