A short-shafted adenoviral fiber and its use

Details A short-shafted adenoviral fiber and its use A short-shafted adenoviral fiber and its use

C - Chemistry, Metallurgy

12

N

C12N 15/86 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07K 14/075 (2006.01) C12N 7/01 (2006.01) C12N 15/861 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2263189

The present invention provides a short-shafted adenoviral fiber, a recombinant adenovirus comprising a short-shafted fiber, a vector comprising a short- shafted adenoviral fiber gene, and a method of targeting attachment of a short- shafted recombinant adenovirus to a cell so as to effect entry of the short- shafted recombinant adenovirus into the cell.

La présente invention a pour objet une fibre adénovirale à tige courte, un adénovirus recombinant comprenant une fibre à tige courte, un vecteur qui inclut un gène ayant une fibre adénovirale à tige courte et une méthode de ciblage de la fixation à une cellule d'un adénovirus recombinant à tige courte qui permet de faire entrer dans la cellule un adénovirus recombinant à tige courte.

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