A simplified method to retrieve chitosan from acidic...

C - Chemistry – Metallurgy – 08 – B

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C08B 37/08 (2006.01) A61K 47/36 (2006.01)

Patent

CA 2551564

Composition of salted out chitosan polymer containing mixture of certain salting out salts as well as methods for making and using same are disclosed. Chitosan polymer preparations produced by such methods are substantially free of chitosanase, undesirable salts and excess acid and retain their physiological as well as biological and physico-chemical properties. The chitosan preparations of the present invention are valuable for the dispensing of biologically active chitosan in forms of drugs or food supplement. Most-of these preparations easily dissolve in an aqueous acidic milieu such as the one of the stomach.

La présente invention concerne une composition constituée d'un mélange contenant des polymères de chitosanes relargués de certains sels de relargage, ainsi que des procédés permettant de les utiliser. Les préparations de polymères de chitosanes produites selon de tels procédés sont essentiellement exemptes de chitosanases, de sels indésirables et d'acide en excès, et elles conservent leurs propriétés physiologiques ainsi que leurs propriétés biologiques et physico-chimiques. Les préparations à base de chitosanes décrites dans cette invention sont particulièrement utiles pour diffuser du chitosane présentant une activité biologique sous forme de médicaments ou de suppléments nutritifs. La plupart de ces préparations se dissolvent facilement dans un milieu acide aqueux, tel que dans l'estomac.

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