A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/36 (2006.01)
Patent
CA 2708400
The present invention relates to a controlled-release pharmaceutical formulation comprising at least one active in-gredient dispersed in a matrix comprising at least one slow-release excipient comprising an association of at least one glycogen and at least one alginate with alkaline-earth metal salts, and a process for its preparation. The invention also relates to a slow-release excipient comprising an association of at least one glycogen and at least one alginate with alkaline-earth metal salts, and the process for its preparation, and its use for the preparation of slow-release pharmaceutical formulations.
La présente invention porte sur une formulation pharmaceutique à libération contrôlée comprenant au moins un ingrédient actif dispersé dans une matrice comprenant au moins un excipient à libération lente comprenant une association d'au moins un glycogène et d'au moins un alginate avec des sels de métal alcalino-terreux, et sur un procédé pour sa préparation. L'invention porte également sur un excipient à libération lente comprenant une association d'au moins un glycogène et d'au moins un alginate avec des sels de métal alcalino-terreux, et sur le procédé pour sa préparation, et sur son utilisation pour la préparation de formulations pharmaceutiques à libération lente.
Cazzolla Nicola
Liberati Elisa
Marchitto Leonardo
Ragni Lorella
Russo Vincenzo
Aziende Chimiche Riunite Angelini Francesco A.c.r.a.f. S.p.a.
Riches Mckenzie & Herbert Llp
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