A stable oxaliplatin solution formulation

Details A stable oxaliplatin solution formulation A stable oxaliplatin solution formulation

A - Human Necessities

61

K

A61K 31/282 (2006.01) A61K 31/13 (2006.01) A61K 47/12 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2468916

The present invention relates to novel stable solution formulations comprising oxaliplatin, an effective stabilizing amount of lactic acid and/or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier. A method for manufacturing such formulations ready for administration and their use in the antitumor therapy are also within the scope of the invention.

L'invention concerne de nouvelles formulations en solution stable renfermant l'oxaliplatine, une dose stabilisante efficace d'acide lactique et/ou un sel de celui-ci pharmaceutiquement acceptable et un vecteur pharmaceutiquement acceptable. L'invention concerne également un procédé de fabrication de telles formulations prêtes à l'emploi et leur utilisation en thérapie antitumorale.

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