A stable pharmaceutical formulation comprising telmisartan...

Details A stable pharmaceutical formulation comprising telmisartan... A stable pharmaceutical formulation comprising telmisartan...

A - Human Necessities

61

K

A61K 31/4184 (2006.01) A61K 9/20 (2006.01) A61K 31/549 (2006.01) A61J 3/00 (2006.01)

Patent

CA 2706292

The present invention is directed to a stable pharmaceutical formulation comprising telmisartan or a pharmaceutically acceptable salt and a diuretic dispersed in a matrix, said matrix comprising: at least one disintegrant in an amount ranging from 0.5 %- 20% by weight; a dissolution enhancing agent present in a molar ratio of dissolution enhancing agent to telmisartan of from 1:1 to 10:1; a water-insoluble diluent in an amount ranging from 15%-75% by weight; and at least one other pharmaceutically acceptable excipient /or adjuvant in an amount ranging from 0 - 25% by weight.

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