A stable pharmaceutical formulation comprising torsemide...

A - Human Necessities – 61 – K

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A61K 31/44 (2006.01) A61K 9/20 (2006.01) A61K 47/12 (2006.01) A61K 47/26 (2006.01) A61K 47/32 (2006.01) A61K 47/38 (2006.01) A61P 7/10 (2006.01) A61P 9/00 (2006.01) A61P 9/12 (2006.01)

Patent

CA 2410802

Novel, stable pharmaceutical formulations for the oral administration of high purity torsemide modification II are disclosed. These formulations release high purity torsemide modification II in water at a constant and high purity rate, and the high purity torsemide modification II therein does not rearrange to torsemide modification I over time. Methods for their manufacture are also disclosed.

L'invention concerne des formulations pharmaceutiques stables pour l'administration orale de torsemide modification II à haute pureté. Ces formulations libèrent du torsemide modification II à haute pureté dans l'eau à un taux constant à haute pureté et le torsemide modification II à haute pureté présent dans l'eau ne réarrange pas le torsemide modification I à la longue. L'invention concerne également des procédés de fabrication desdites formulations.

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