A stable pharmaceutical formulation comprising torsemide...

A - Human Necessities – 61 – K

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A61K 9/00 (2006.01) A01N 43/40 (2006.01) A61K 9/20 (2006.01) C07D 213/74 (2006.01)

Patent

CA 2455881

Novel, stable pharmaceutical formulations for the oral administration of high purity torsemide modification II are disclosed. These formulations release high purity torsemide modification II in water at a constant and high purity rate, and the high purity torsemide modification II therein does not rearrange to torsemide modification I over time. Methods for their manufacture are also disclosed.

L'invention concerne des nouvelles formulations pharmaceutiques stables destinées à une administration orale de torsemide de modification II de grande pureté. Ces formulations libèrent du torsemide de modification II de grande pureté dans de l'eau à un taux de pureté constant et élevé, et ledit torsemide de modification II de grande pureté ne se réagence pas en torsemide de modification I avec le temps. L'invention concerne également des procédés de production associés.

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