A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4525 (2006.01) A61J 3/10 (2006.01) A61K 9/20 (2006.01) A61K 9/28 (2006.01) A61K 47/30 (2006.01)
Patent
CA 2470496
Provided are formulations of a stable paroxetine hydrochloride tablet comprising paroxetine hydrochloride, povidone or copovidone as a binder, and an HCl free/non-hygroscopic filler, prepared by the wet granulation method. Preferably, the paroxetine hydrochloride is paroxetine hydrochloride hemihydrate.
La présente invention concerne des formulations de comprimés d'hydrochlorure de paroxétine stable comprenant de l'hydrochlorure de paroxétine, de la povidone ou de la copovidone comme liant, et une charge sans HCI/non hygroscopique, que l'on prépare selon le procédé de granulation par voie humide. De préférence, l'hydrochlorure de paroxétine est un hémihydrate d'hydrochlorure de paroxétine.
Cohen Rakefet
Fox Michael
Heenan Blaikie Llp
Teva Pharmaceutical Industries Ltd.
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