A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/04 (2006.01) A61K 38/05 (2006.01) A61K 38/55 (2006.01) C07K 5/02 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2203396
This invention relates to a storage stable concentrated water-solution for infusion having a pH in the range from 1.0 to 2.5 and containing an active thrombin inhibitor having the formula: HOOC-CH2-Y, wherein Y is (R)-Cha-Pic- Nag or (R)-Cgl-Aze-Pab, as a salt or as a free base thereof, a process for their preparation and to a method for treatment of a patient in need of said formulation.
Solution aqueuse concentrée stable au stockage, destinée à être injectée, qui possède un pH allant de 1,0 à 2,5 et qui contient un inhibiteur actif de thrombine de formule HOOC-CH¿2?-Y, dans laquelle Y est (R)-Cha-Pic-Nag ou (R)-Cgl-Aze-Pab, ou sel ou base libre dudit inhibiteur, procédé de préparation dudit inhibiteur et procédé de traitement d'un patient nécessitant un remède de ce type.
Stjernfeit Ulla
Sundgren Mats
Astra Aktiebolag
Fetherstonhaugh & Co.
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