C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/071 (2010.01) C12N 5/0775 (2010.01) A61K 38/10 (2006.01) A61K 38/18 (2006.01) C07K 14/51 (2006.01) C12N 5/02 (2006.01)
Patent
CA 2681317
Disclosed herein is an osteogenic synthetic peptide, derived from bone morphogenetic protein-7, consisting of a sequence of 15 amino acid residues (BFP 1). Provided are also a pharmaceutical composition and a medium composition comprising the same. Having remarkable activity related to promoting osteoblast differentiation, the osteogenic synthetic peptide is very useful in the treatment of osteoporosis, bone defects and/or osteoarthritis.
La présente invention concerne un peptide synthétique ostéogène, dérivé de la protéine morphogénétique osseuse 7, composée d'une séquence de 15 résidus d'acide aminé (BFP 1). L'invention concerne également une composition pharmaceutique et une composition de milieu la comprenant. Doté d'une activité remarquable favorisant la différentiation ostéoblastique, le peptide synthétique ostéogène est très utile dans le traitement de l'ostéoporose, des pertes de substance osseuse et/ou de l'arthrose.
Kim Hyung Keun
Kim Ji Hyun
Yoon Taek Rim
Goudreau Gage Dubuc
Industry Foundation Of Chonnam National University
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