A system for cell-based screening

G - Physics – 01 – N

Patent

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Details

G01N 33/58 (2006.01) G01N 15/14 (2006.01) G01N 33/50 (2006.01) G01N 33/533 (2006.01) G01N 33/566 (2006.01) G01N 35/00 (2006.01) G01N 35/04 (2006.01)

Patent

CA 2328194

The present invention provides systems, methods, and screens to measure receptor internalization in a single step with appropriate automation and throughput. This approach involves luminescent labeling of the receptor of interest and the automated measurement of receptor internalization to a perinuclear location.

La présente invention concerne des systèmes, des procédés et des techniques de criblage qui servent à mesurer l'internalisation à un stade individuel avec une automatisation et un débit appropriés. Les procédés et techniques de l'invention nécessitent le marquage luminescent du récepteur d'intérêt et la mesure automatisée de l'internalisation de récepteurs vers un emplacement périnucléaire.

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