A system for inducible expression in eukaryotic cells

Details A system for inducible expression in eukaryotic cells A system for inducible expression in eukaryotic cells

C - Chemistry, Metallurgy

12

N

C12N 15/78 (2006.01) A61K 48/00 (2006.01) C12N 15/31 (2006.01) C12N 15/79 (2006.01) C12N 15/85 (2006.01) C12N 15/86 (2006.01)

Patent

CA 2446110

The invention relates to a new "gene-switch" (cumate-inducible switch) for mammalian cells. This switch is as useful in the development of expression systems and cell-based assays for functional genomics as in the generation of viral vectors for gene therapy.

L'invention concerne un nouveau "commutateur génétique" (commutateur inductible par cumate) destiné aux cellules mammaliennes. Ce commutateur est utile dans le développement des systèmes d'expression et des dosages basés sur des cellules et destinés à la génomique fonctionnelle tout comme dans la génération de vecteurs viraux destinés à la thérapie génique.

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