A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/164
A61K 47/30 (2006.01) A01N 25/26 (2006.01) A61K 9/00 (2006.01) A61K 9/20 (2006.01) A61K 9/28 (2006.01) A61K 9/52 (2006.01)
Patent
CA 2009045
22 A System for the Controlled Release of Active Agents and a Process for its Preparation Abstract The invention relates to a system for the controlled release of active agents and a process for its preparation, pref- erably an orally administrable pharmaceutical preparation for various, especially soluble, pharmaceutical agents, hav- ing even, controlled active agent release essentially caused by convective processes. The system of the invention is similar in therapeutic effec- tivity to an intravenous drip, i.e. the even and complete release of the active agent from the pharmaceutical prepara- tion for a physiologically and therapeutically practical period of time caused by essentially convective processes. This leads to a constant therapeutic blood level which gua- rantees the long-term effect of the drug whilst reducing the adverse effects and improving local tolerance in the gas- trointestinal tract at the same time. Furthermore, with the composition according to the invention of the pharmaceutical preparation and the preparation pro- cess according to the invention, damages to the shell con- trolling the release of the pharmaceutical agent will not lead to dose-dumping, as is usually the case in membrane- controlled pharmaceutical agent release, and the preset re- lease rate will be reached within a short period of time.
Jaeger Halvor
Metzner Jurgen
Rosin Thomas
Salama Zoser B.
Wenzel Udo
Ipa Internationale Pharma Agentur G.m.b.h
Kirby Eades Gale Baker
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