A therapeutic agent for ischemic diseases

A - Human Necessities – 61 – K

Patent

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A61K 35/12 (2006.01) A61K 35/36 (2006.01)

Patent

CA 2270050

The invention relates to a therapeutic agent for ischemic diseases having little side effects and being capable of administering safely. The effective component of the therapeutic agent for ischemic diseases of the present invention is an extract from inflammatory tissue inoculated with vaccinia virus. An extract from inflammatory tissue inoculated with vaccinia virus. protects a cell against damage by suppressing abnormal depolarization of hippocampal pyramidal neurons during hypoxia and so can delay the time falling into cell death. The characteristic action is not observed for normal pyramidal neurons, but is expressed only in the stage of pathema during hypoxia. Therefore, the substance of the present invention is useful as a drug to treat and prevent ischemic diseases such as cerebral infarction and the like and symptoms accompanying with neuropathy caused by ischemia.

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