A thymus-specific protein

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/52 (2006.01) C07K 14/715 (2006.01) C12N 1/21 (2006.01) C12N 15/12 (2006.01) C12N 15/19 (2006.01)

Patent

CA 2585364

The invention provides the novel thymus-specific human protein T101, an 84- amino acid polypeptide isolated from the human thymus. The full T101 peptide contains a 33-amino acid signal peptide and a 51-amino acid T101 peptide sequence with both immune stimulatory and inhibitory activities. Also provided are modified peptides and partial T101 peptide sequences.

La présente invention concerne la nouvelle protéine humaine spécifique au thymus T101, un polypeptide à 84 acides aminés isolé du thymus humain. Le peptide T101 complet contient un peptide signal à 33 acides aminés et une séquence peptidique T101 à 51 acides aminés présentant des activités de stimulation et d'inhibition de l'immunité. Cette invention se rapporte également à des peptides modifiés et à des séquences de peptide T101 partiel.

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