A treatment for necrotizing enterocolitis

Details A treatment for necrotizing enterocolitis A treatment for necrotizing enterocolitis

A - Human Necessities

61

K

A61K 38/18 (2006.01) A61K 31/04 (2006.01) A61K 31/198 (2006.01) A61P 1/00 (2006.01)

Patent

CA 2548773

The invention provides compositions and methods for the treatment of necrotizing enterocolitis (NEC). A treatment of epidermal growth factor (EGF) receptor agonist and L-arginine, a bioequivalent thereof, or NO-donor showed efficacy against NEC. The invention also provides kits, unit doses and uses comprising epidermal growth factor (EGF) receptor agonist and L-arginine, a bioequivalent thereof, or NO-donor for the treatment of NEC.

L'invention concerne des compositions et procédés destinés au traitement de l'entérocolite nécrosante néonatale (NEC). Un traitement utilisant l'agoniste des récepteurs du facteur de croissance épidermique (EGF) et la L-arginine, ou son bioequivalent, dans lequel un donneur NO s'est montré efficace contre NEC. L'invention concerne aussi des kits, des unités posologiques et des procédés d'utilisation comprenant l'agoniste des récepteurs du facteur de croissance épidermique (EGF) et la L-arginine, ou son bioequivalent, dans lequel un donneur NO s'est montré efficace contre NEC.

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