A treatment simulator for brain diseases and method of use...

A - Human Necessities – 61 – B

Patent

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A61B 5/00 (2006.01) G06Q 50/22 (2012.01) A61B 5/03 (2006.01) A61B 6/00 (2006.01)

Patent

CA 2687330

A treatment simulator for providing information on physiological states and effects of treatment of neurological disease, comprising a computer, and an application configured to operate with the computer. The application is capable of: obtaining radiological imaging from the brain; obtaining anatomical information from the radiological imaging within a region of interest within the brain; constructing a physiological states model which assesses physiological states of the region of interest; locating sources of interstitial flow of particulate matter and obtaining fluid conductivities of paths of the interstitial flow utilizing the anatomical information and the physiological states model; and creating a flow model of the particulate matter which assesses velocities of flow and interstitial pressure variations utilizing the sources of interstitial flow and the fluid conductivities.

L'invention concerne un simulateur de traitement pour fournir des informations sur des états physiologiques et les effets du traitement d'une maladie neurologique, comprenant un ordinateur et une application conçue pour fonctionner avec l'ordinateur. L'application est capable: d'obtenir une imagerie radiologique du cerveau ; d'obtenir des informations anatomiques à partir de l'imagerie radiologique d'une région d'intérêt à l'intérieur du cerveau ; de construire un modèle d'états physiologiques qui évalue les états physiologiques de la région d'intérêt ; de situer des sources d'un flux interstitiel de matière particulaire et d'obtenir des conductivités de liquide des passages du flux interstitiel en utilisant les informations anatomiques et le modèle d'états physiologiques ; et de créer un modèle de flux de la matière particulaire qui évalue les vélocités de flux et les variations de pression interstitielle en utilisant les sources de flux interstitiel et les conductivités de liquide.

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