A variant form of urate oxidase and use thereof

Details A variant form of urate oxidase and use thereof A variant form of urate oxidase and use thereof

C - Chemistry, Metallurgy

12

N

C12N 9/72 (2006.01)

Patent

CA 2604545

The present invention relates to genetically modified proteins with uricolytic activity. More specifically, the invention relates to proteins comprising truncated urate oxidases and methods for producing them, including PEGylated proteins comprising truncated urate oxidases.

La présente invention concerne des protéines génétiquement modifiées dotées d'une activité uricolytique. Plus spécifiquement, cette invention a pour objet des protéines contenant des oxydases d'urate tronquées et leurs méthodes de production, y compris, des protéines pégylées renfermant des oxydases d'urate tronquées.

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