A vector expressing an rna viral full-length gene and its use

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/85 (2006.01) C12N 5/10 (2006.01) C12N 7/00 (2006.01) C12N 15/10 (2006.01) C12N 15/40 (2006.01) C12N 15/51 (2006.01) C12N 15/66 (2006.01) C12Q 1/70 (2006.01) A01K 67/027 (2006.01) C07K 14/18 (2006.01)

Patent

CA 2330837

This invention provides a vector comprising cDNA encoding an RNA viral gene, characterized in that the vector is constructed such that both termini of the RNA viral gene can be transcribed precisely and uniformly. This vector is useful to elucidate the mechanisms of RNA virus replication and of the development of RNA virus infections, and to develop therapeutic agents and means of treatment, and so on.

L'invention concerne un vecteur contenant un ADNc qui code pour un gène de virus à ARN et qui a été construit de façon à assurer la transcription exacte et homogène des deux extrémités dudit gène. Ce vecteur est utile pour clarifier le mécanisme de la réplication du virus à ARN, clarifier le mécanisme du début de l'infection par ledit virus, développer des médicaments et des moyens thérapeutiques contre ladite infection, etc.

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