A2a receptor agonists

Details A2a receptor agonists A2a receptor agonists

C - Chemistry, Metallurgy

07

H

C07H 19/16 (2006.01) A61K 31/7076 (2006.01) A61K 49/00 (2006.01) A61P 9/00 (2006.01)

Patent

CA 2373410

2-Adenosine thiophene compounds having the formula (I): and methods for using the compounds as A2A receptor agonists to stimulate mammalian coronary vasodilatation for therapeutic purposes and for purposes of imaging the heart.

L'invention concerne des composés de 2-adénosine thiophène représentés par la formule (I) ; ainsi que des méthodes d'utilisation de ces composés en tant qu'agonistes du récepteur A2A pour stimuler la vasodilatation coronaire chez des mammifères à des fins thérapeutiques et d'imagerie du coeur.

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