Aatt promoter element and transcription factor

Details Aatt promoter element and transcription factor Aatt promoter element and transcription factor

C - Chemistry, Metallurgy

12

N

C12N 15/67 (2006.01) C07K 14/415 (2006.01) C07K 16/16 (2006.01) C12N 9/88 (2006.01) C12N 15/11 (2006.01) C12N 15/29 (2006.01) C12N 15/82 (2006.01)

Patent

CA 2261029

A novel transcription enhancer element, (AATT)n, that increases the activity of cis-elements in heterologous promoter constructs without altering their intrinsic specificity is provided. Also provided is a transcription factor, PABF, which specifically binds to the (AATT) repeat element and methods of use therefor.

L'invention concerne un nouvel activateur de transcription, (AATT)¿n?, qui accroît l'activité des éléments cis dans les produits de synthèse promoteurs hétérologues, sans en modifier la spécificité propre. On décrit un facteur de transcription, le facteur de liaison de palindrome (PABF), qui se lie spécifiquement à la répétition (AATT), et les procédés d'utilisation correspondants.

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