A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 31/7088 (2006.01) A61K 38/18 (2006.01) A61K 38/44 (2006.01) A61K 38/51 (2006.01) C12N 15/864 (2006.01) C12N 9/02 (2006.01) C12N 9/88 (2006.01) C12N 15/53 (2006.01) C12N 15/60 (2006.01)
Patent
CA 2187626
The invention relates to a method of delivering exogenous DNA to a target cell of the mammalian central nervous system using an adeno-associated virus (AAV)-derived vector. Also included in the invention are the AAV-derived vectors containing exogenous DNA which encodes a protein or proteins which prevent or treat nervous system disease, and a method of preventing or treating such disease.
L'invention porte sur une méthode de transmission d'ADN exogène à une cellule cible du système nerveux central d'un mammifère par le biais d'un vecteur dérivé d'un virus adénoassocié (AAV). L'invention porte également sur lesdits vecteurs contenant l'ADN exogène codant pour une ou des protéines prévenant ou traitant les maladies du système nerveux central et sur les méthodes de prévention et de traitement associées.
During Matthew J.
Kaplitt Michael G.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Rockefeller University (the)
Yale University
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